{"id":16052,"date":"2020-06-18T15:32:03","date_gmt":"2020-06-18T15:32:03","guid":{"rendered":"https:\/\/sbpt.org.br\/portal\/?p=16052"},"modified":"2020-06-18T15:32:03","modified_gmt":"2020-06-18T15:32:03","slug":"dexametasona-covid-sbpt","status":"publish","type":"post","link":"https:\/\/sbpt.org.br\/portal\/dexametasona-covid-sbpt\/","title":{"rendered":"Comunicado da SBPT sobre o uso de dexametasona no tratamento da COVID-19"},"content":{"rendered":"<p><em>Bras\u00edlia, 18 de junho de 2020<\/em><\/p>\n<p style=\"text-align: justify\">Anteontem (16\/06\/2020), a Universidade de Oxford divulgou os resultados preliminares do estudo randomizado <a href=\"https:\/\/www.recoverytrial.net\/\" target=\"_blank\" rel=\"noopener noreferrer\">RECOVERY<\/a> (Randomised Evaluation of COVID-19 Therapy). Os dados divulgados indicam que pacientes com COVID-19 sob ventila\u00e7\u00e3o mec\u00e2nica podem se beneficiar da terapia com dexametasona.<\/p>\n<p style=\"text-align: justify\">A descoberta representa um avan\u00e7o importante. No entanto, \u00e9 preciso cautela. Por se tratar de uma medica\u00e7\u00e3o de baixo custo e f\u00e1cil acesso, a informa\u00e7\u00e3o divulgada pelos estudiosos brit\u00e2nicos pode gerar uma \u201ccorrida\u201d pela dexametasona e uso indiscriminado da medica\u00e7\u00e3o sem orienta\u00e7\u00e3o m\u00e9dica.<\/p>\n<p style=\"text-align: justify\">Tal cen\u00e1rio seria desastroso, pois os efeitos adversos da droga podem ser ainda mais perigosos do que a COVID-19, desencadeando outras doen\u00e7as e agravando a sobrecarga nos hospitais.<\/p>\n<p style=\"text-align: justify\">O uso de dexametasona j\u00e1 foi associado a dist\u00farbios hidroeletrol\u00edticos, altera\u00e7\u00f5es m\u00fasculoesquel\u00e9ticas e gastrintestinais, rea\u00e7\u00f5es dermatol\u00f3gicas, dist\u00farbios psiqui\u00e1tricos e danos nos sistemas end\u00f3crino, oft\u00e1lmico, metab\u00f3lico, imunol\u00f3gico, hematol\u00f3gico e cardiovascular. Por isso, <strong><u>a SBPT reitera que o uso de dexametasona sem orienta\u00e7\u00e3o m\u00e9dica n\u00e3o \u00e9 seguro.<\/u><\/strong><\/p>\n<p style=\"text-align: justify\">Al\u00e9m disso, de acordo com os pesquisadores do RECOVERY, <u>nos pacientes com COVID-19 que n\u00e3o necessitavam de oxig\u00eanio, n\u00e3o houve sinais de recupera\u00e7\u00e3o com o uso da medica\u00e7\u00e3o.<\/u> Os resultados preliminares constataram que houve redu\u00e7\u00e3o da mortalidade apenas em pacientes com COVID-19 sob ventila\u00e7\u00e3o mec\u00e2nica ou suporte de oxig\u00eanio. Nestes casos, ministrar 6 mg de dexametasona (por via oral ou endovenosa) 1x\/dia por 10 dias resultou em diminui\u00e7\u00e3o de mortalidade de 33,3% dos pacientes com COVID-19 sob ventila\u00e7\u00e3o mec\u00e2nica e de 20% dos pacientes com suporte de oxig\u00eanio fora da Terapia Intensiva (em 28 dias).<\/p>\n<p style=\"text-align: justify\">Mesmo para pacientes com essas caracter\u00edsticas, a ado\u00e7\u00e3o dessa terapia deve ser discutida caso a caso enquanto esperamos a publica\u00e7\u00e3o dos resultados do estudo RECOVERY. <strong>A leitura cuidadosa e cr\u00edtica do estudo publicado \u00e9 fundamental.<\/strong><\/p>\n<p><em>Diretoria da SBPT<\/em>.<\/p>\n<p><a href=\"https:\/\/d1xe7tfg0uwul9.cloudfront.net\/sbpt-portal\/wp-content\/uploads\/2020\/06\/dexametasona_covid_sbpt.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Clique aqui para fazer download deste comunicado em PDF.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Bras\u00edlia, 18 de junho de 2020 Anteontem (16\/06\/2020), a Universidade de Oxford divulgou os resultados preliminares do estudo randomizado RECOVERY (Randomised Evaluation of COVID-19 Therapy). Os dados divulgados indicam que pacientes com COVID-19 sob ventila\u00e7\u00e3o mec\u00e2nica podem se beneficiar da terapia com dexametasona. A descoberta representa um avan\u00e7o importante. No entanto, \u00e9 preciso cautela. Por [\u2026]","protected":false},"author":3,"featured_media":12084,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"ngg_post_thumbnail":0,"footnotes":""},"categories":[68],"tags":[118,838,31,839,840],"class_list":["post-16052","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias","tag-covid-19","tag-dexametasona","tag-pneumologia","tag-recovery","tag-universidade-de-oxford"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Comunicado da SBPT sobre o uso de dexametasona no tratamento da COVID-19<\/title>\n<meta name=\"description\" content=\"Anteontem (16\/06\/2020), a Universidade de Oxford divulgou os resultados preliminares do estudo randomizado RECOVERY (Randomised Evaluation of COVID-19 Therapy). 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