{"id":15611,"date":"2020-05-20T14:49:11","date_gmt":"2020-05-20T14:49:11","guid":{"rendered":"https:\/\/sbpt.org.br\/portal\/?p=15611"},"modified":"2020-05-20T14:49:11","modified_gmt":"2020-05-20T14:49:11","slug":"heparina-covid-19","status":"publish","type":"post","link":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/","title":{"rendered":"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">A Dra. Elnara\nNegri e a equipe de m\u00e9dicos do Hospital S\u00edrio-Liban\u00eas trataram 27 pacientes\ninternados com COVID-19 com heparina em doses adaptadas \u00e0 gravidade cl\u00ednica.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Como\nresultado, o uso da medica\u00e7\u00e3o foi associado a uma menor taxa de mortalidade:\n81% recebeu alta em casa em um tempo m\u00e9dio de 11,4 dias e a maioria dos\npacientes sob ventila\u00e7\u00e3o mec\u00e2nica (67%) foi extubada em cerca de 12,5 dias. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Em entrevista a duas importantes revistas cient\u00edficas internacionais \u2013 <a href=\"https:\/\/www.sciencemag.org\/news\/2020\/04\/why-don-t-some-coronavirus-patients-sense-their-alarmingly-low-oxygen-levels\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">Science<\/a> e <a href=\"https:\/\/www.nature.com\/articles\/d41586-020-01355-z\">Nature<\/a>, a Dra. Elnara explicou que h\u00e1 possibilidade de haver uma resposta de hipercoagula\u00e7\u00e3o logo no in\u00edcio da infec\u00e7\u00e3o, causando uma rea\u00e7\u00e3o inflamat\u00f3ria nos vasos sangu\u00edneos, seguida da forma\u00e7\u00e3o de microtrombos que impedem que o sangue seja oxigenado adequadamente.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cO d-d\u00edmero\nelevado \u00e9 um indicador de severidade e mortalidade em pacientes com COVID-19 e\nas aut\u00f3psias dos pacientes infectados revelaram trombos na microcircula\u00e7\u00e3o\u201d,\nrelata a autora. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cCuriosamente,\nna COVID-19, na maioria dos pacientes, a complac\u00eancia pulmonar \u00e9 preservada,\napesar da hipoxemia grave, corroborando com a hip\u00f3tese de que a redu\u00e7\u00e3o da\nperfus\u00e3o alveolar pode desempenhar um papel significativo no desenvolvimento de\ninsufici\u00eancia respirat\u00f3ria\u201d, completa.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Em entrevista \u00e0 <a href=\"http:\/\/agencia.fapesp.br\/covid-19-deve-ser-tratada-como-uma-doenca-trombotica-afirma-medica-brasileira\/33175\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">Ag\u00eancia FAPESP<\/a> em 15\/05\/2020, a Dra. Negri detalha a descoberta: o SARS-CoV-2 induz \u00e0 descama\u00e7\u00e3o do tecido epitelial no interior dos alv\u00e9olos, deixando a membrana basal exposta. A tempestade inflamat\u00f3ria \u00e9 seguida pela ativa\u00e7\u00e3o da cascata de coagula\u00e7\u00e3o, coma forma\u00e7\u00e3o de microtrombos inicialmente na microcircula\u00e7\u00e3o pulmonar, podendo progredir para outros \u00f3rg\u00e3os.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Os co\u00e1gulos\nacabam obstruindo pequenos vasos do pulm\u00e3o e causando microinfartos. As regi\u00f5es\ndo tecido que morrem por falta de irriga\u00e7\u00e3o d\u00e3o lugar a tecido cicatricial.\nAl\u00e9m disso, os microtrombos que se formam na interface do alv\u00e9olo com os vasos\nsangu\u00edneos impedem a passagem do oxig\u00eanio para as pequenas art\u00e9rias.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A Dra. Negri\ndefende que a interven\u00e7\u00e3o com anticoagulante comece assim que se comprove que a\nsatura\u00e7\u00e3o de oxig\u00eanio est\u00e1 abaixo de 93%, o que pode ocorrer entre o s\u00e9timo e o\n10\u00ba dia ap\u00f3s o in\u00edcio dos sintomas gripais, que podem ser diagnosticados pelo\nm\u00e9dico no consult\u00f3rio ou Unidade B\u00e1sica de Sa\u00fade (UBS). <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A pesquisadora\nalerta, ainda, para os riscos da automedica\u00e7\u00e3o: \u201ccomprar o rem\u00e9dio na farm\u00e1cia\ne tomar por via oral n\u00e3o tem efeito terap\u00eautico e ainda pode induzir uma\nhemorragia. O tratamento deve ser injet\u00e1vel e a dose ajustada pelo m\u00e9dico\u201d.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">O estudo da Dra. Elnara Negri est\u00e1 dispon\u00edvel na <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.04.15.20067017v3\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">plataforma medRxiv<\/a> ainda em vers\u00e3o preprint (sem revis\u00e3o por pares). <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A pr\u00f3xima\netapa \u00e9 iniciar o projeto de comprova\u00e7\u00e3o da efic\u00e1cia da heparina no tratamento\nda COVID-19, por meio de ensaio cl\u00ednico randomizado, e observar se a terapia\npode evitar a ventila\u00e7\u00e3o mec\u00e2nica em alguns casos. Para isso, os pesquisadores\nda FM-USP planejam uma parceria com grupos das Universidades de Toronto e\nAmsterd\u00e3. <\/p>\n\n\n\n<hr class=\"wp-block-separator\" \/>\n\n\n\n<p class=\"wp-block-paragraph\">A Dra. Elnara\nNegri \u00e9 m\u00e9dica pesquisadora dos laborat\u00f3rios de Investiga\u00e7\u00e3o M\u00e9dica da\nFaculdade de Medicina da Universidade de S\u00e3o Paulo e pneumologista do N\u00facleo\nAvan\u00e7ado de T\u00f3rax do Hospital S\u00edrio Liban\u00eas. Tem 30 anos de experi\u00eancia cl\u00ednica,\natuando principalmente em medicina intensiva, broncoscopia e pneumologia.\nLinhas de pesquisa: remodelamento pulmonar na insufici\u00eancia respirat\u00f3ria e\nmecanismos de defesa pulmonar, DPOC e c\u00e2ncer de pulm\u00e3o. \u00c9 pneumologista s\u00f3cia\nda SBPT desde 1995.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Veja mais:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">TOLEDO, Karina. <a href=\"http:\/\/agencia.fapesp.br\/covid-19-deve-ser-tratada-como-uma-doenca-trombotica-afirma-medica-brasileira\/33175\/\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">COVID-19 deve ser tratada como uma doen\u00e7a tromb\u00f3tica, afirma m\u00e9dica brasileira<\/a>. Ag\u00eancia FAPESP. 15 mai 2020. Dispon\u00edvel em: &lt;http:\/\/agencia.fapesp.br\/covid-19-deve-ser-tratada-como-uma-doenca-trombotica-afirma-medica-brasileira\/33175\/&gt;;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">LEDFORD, Heidi. <a href=\"https:\/\/www.nature.com\/articles\/d41586-020-01355-z\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">Autopsy slowdown hinders quest to determine how coronavirus kills<\/a>. Revista Nature. 7 mai 2020. Dispon\u00edvel em: &lt; https:\/\/www.nature.com\/articles\/d41586-020-01355-z&gt;;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NEGRI, E.M, et al. <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.04.15.20067017v3\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">Heparin therapy improving hypoxia in COVID-19 patients &#8211; a case series<\/a>. medRxiv 2020.04.15.20067017; doi: <a href=\"https:\/\/doi.org\/10.1101\/2020.04.15.20067017\">https:\/\/doi.org\/10.1101\/2020.04.15.20067017<\/a>. 30 abr 2020.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">COUZIN-FRANKEL, Jennifer. <a href=\"https:\/\/www.sciencemag.org\/news\/2020\/04\/why-don-t-some-coronavirus-patients-sense-their-alarmingly-low-oxygen-levels\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">Why don\u2019t some coronavirus patients sense their alarmingly low oxygen levels?<\/a>. Revista Science. 28 abr 2020. Dispon\u00edvel em: &lt; https:\/\/www.sciencemag.org\/news\/2020\/04\/why-don-t-some-coronavirus-patients-sense-their-alarmingly-low-oxygen-levels&gt;;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sociedade Brasileira de Pneumologia e Tisiologia. <a href=\"https:\/\/youtu.be\/GY5wuOtUEvU\" target=\"_blank\" rel=\"noreferrer noopener\" aria-label=\" (opens in a new tab)\">Debates Interativos SBPT &#8211; Tratamento de suporte, medicamentos a serem considerados, estudos cl\u00ednicos e indicadores de evolu\u00e7\u00e3o<\/a>. 16 abr 2020. Dispon\u00edvel em: &lt;https:\/\/youtu.be\/GY5wuOtUEvU&gt;.<\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>A Dra. Elnara Negri e a equipe de m\u00e9dicos do Hospital S\u00edrio-Liban\u00eas trataram 27 pacientes internados com COVID-19 com heparina em doses adaptadas \u00e0 gravidade cl\u00ednica. Como resultado, o uso da medica\u00e7\u00e3o foi associado a uma menor taxa de mortalidade: 81% recebeu alta em casa em um tempo m\u00e9dio de 11,4 dias e a maioria [&hellip;]<!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":3,"featured_media":14596,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"ngg_post_thumbnail":0,"footnotes":""},"categories":[68],"tags":[117],"class_list":["post-15611","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias","tag-coronavirus"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave - sbpt.org.br<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave - sbpt.org.br\" \/>\n<meta property=\"og:description\" content=\"A Dra. Elnara Negri e a equipe de m\u00e9dicos do Hospital S\u00edrio-Liban\u00eas trataram 27 pacientes internados com COVID-19 com heparina em doses adaptadas \u00e0 gravidade cl\u00ednica. Como resultado, o uso da medica\u00e7\u00e3o foi associado a uma menor taxa de mortalidade: 81% recebeu alta em casa em um tempo m\u00e9dio de 11,4 dias e a maioria [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/\" \/>\n<meta property=\"og:site_name\" content=\"sbpt.org.br\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/pneumosbpt\" \/>\n<meta property=\"article:published_time\" content=\"2020-05-20T14:49:11+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2020\/01\/coronavirus-destaque.png\" \/>\n\t<meta property=\"og:image:width\" content=\"350\" \/>\n\t<meta property=\"og:image:height\" content=\"255\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Comunica\u00e7\u00e3o SBPT\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@pneumosbpt\" \/>\n<meta name=\"twitter:site\" content=\"@pneumosbpt\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Comunica\u00e7\u00e3o SBPT\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/\"},\"author\":{\"name\":\"Comunica\u00e7\u00e3o SBPT\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#\\\/schema\\\/person\\\/adba7f33cf32721354590c6f0eb852d4\"},\"headline\":\"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave\",\"datePublished\":\"2020-05-20T14:49:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/\"},\"wordCount\":753,\"publisher\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/coronavirus-destaque.png\",\"keywords\":[\"coronav\u00edrus\"],\"articleSection\":[\"Not\u00edcias\"],\"inLanguage\":\"pt-BR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/\",\"url\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/\",\"name\":\"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave - sbpt.org.br\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/coronavirus-destaque.png\",\"datePublished\":\"2020-05-20T14:49:11+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/#primaryimage\",\"url\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/coronavirus-destaque.png\",\"contentUrl\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/coronavirus-destaque.png\",\"width\":350,\"height\":255},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/heparina-covid-19\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#website\",\"url\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/\",\"name\":\"sbpt.org.br\",\"description\":\"Sociedade Brasileira de Pneumologia e Tisiologia\",\"publisher\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#organization\"},\"alternateName\":\"SBPT\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#organization\",\"name\":\"sbpt.org.br\",\"url\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/wp-content\\\/uploads\\\/2026\\\/10\\\/logo-sbpt.png\",\"contentUrl\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/wp-content\\\/uploads\\\/2026\\\/10\\\/logo-sbpt.png\",\"width\":512,\"height\":512,\"caption\":\"sbpt.org.br\"},\"image\":{\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/pneumosbpt\",\"https:\\\/\\\/x.com\\\/pneumosbpt\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/pneumosbpt\\\/\",\"https:\\\/\\\/www.instagram.com\\\/pneumosbpt\\\/\",\"https:\\\/\\\/www.youtube.com\\\/user\\\/socbraspneumol\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/#\\\/schema\\\/person\\\/adba7f33cf32721354590c6f0eb852d4\",\"name\":\"Comunica\u00e7\u00e3o SBPT\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/83068fab2f784f5c487104783a7006fb40e8fd85adc44189ac928b9e39fddad8?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/83068fab2f784f5c487104783a7006fb40e8fd85adc44189ac928b9e39fddad8?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/83068fab2f784f5c487104783a7006fb40e8fd85adc44189ac928b9e39fddad8?s=96&d=mm&r=g\",\"caption\":\"Comunica\u00e7\u00e3o SBPT\"},\"url\":\"https:\\\/\\\/sbpt.org.br\\\/portal\\\/author\\\/anahelena\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave - sbpt.org.br","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/","og_locale":"pt_BR","og_type":"article","og_title":"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave - sbpt.org.br","og_description":"A Dra. Elnara Negri e a equipe de m\u00e9dicos do Hospital S\u00edrio-Liban\u00eas trataram 27 pacientes internados com COVID-19 com heparina em doses adaptadas \u00e0 gravidade cl\u00ednica. Como resultado, o uso da medica\u00e7\u00e3o foi associado a uma menor taxa de mortalidade: 81% recebeu alta em casa em um tempo m\u00e9dio de 11,4 dias e a maioria [&hellip;]","og_url":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/","og_site_name":"sbpt.org.br","article_publisher":"https:\/\/www.facebook.com\/pneumosbpt","article_published_time":"2020-05-20T14:49:11+00:00","og_image":[{"width":350,"height":255,"url":"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2020\/01\/coronavirus-destaque.png","type":"image\/png"}],"author":"Comunica\u00e7\u00e3o SBPT","twitter_card":"summary_large_image","twitter_creator":"@pneumosbpt","twitter_site":"@pneumosbpt","twitter_misc":{"Escrito por":"Comunica\u00e7\u00e3o SBPT","Est. tempo de leitura":"4 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/#article","isPartOf":{"@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/"},"author":{"name":"Comunica\u00e7\u00e3o SBPT","@id":"https:\/\/sbpt.org.br\/portal\/#\/schema\/person\/adba7f33cf32721354590c6f0eb852d4"},"headline":"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave","datePublished":"2020-05-20T14:49:11+00:00","mainEntityOfPage":{"@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/"},"wordCount":753,"publisher":{"@id":"https:\/\/sbpt.org.br\/portal\/#organization"},"image":{"@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/#primaryimage"},"thumbnailUrl":"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2020\/01\/coronavirus-destaque.png","keywords":["coronav\u00edrus"],"articleSection":["Not\u00edcias"],"inLanguage":"pt-BR"},{"@type":"WebPage","@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/","url":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/","name":"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave - sbpt.org.br","isPartOf":{"@id":"https:\/\/sbpt.org.br\/portal\/#website"},"primaryImageOfPage":{"@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/#primaryimage"},"image":{"@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/#primaryimage"},"thumbnailUrl":"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2020\/01\/coronavirus-destaque.png","datePublished":"2020-05-20T14:49:11+00:00","breadcrumb":{"@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/"]}]},{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/#primaryimage","url":"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2020\/01\/coronavirus-destaque.png","contentUrl":"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2020\/01\/coronavirus-destaque.png","width":350,"height":255},{"@type":"BreadcrumbList","@id":"https:\/\/sbpt.org.br\/portal\/heparina-covid-19\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/sbpt.org.br\/portal\/"},{"@type":"ListItem","position":2,"name":"Pneumologista brasileira observa que o tratamento com heparina melhora a hip\u00f3xia na COVID-19 grave"}]},{"@type":"WebSite","@id":"https:\/\/sbpt.org.br\/portal\/#website","url":"https:\/\/sbpt.org.br\/portal\/","name":"sbpt.org.br","description":"Sociedade Brasileira de Pneumologia e Tisiologia","publisher":{"@id":"https:\/\/sbpt.org.br\/portal\/#organization"},"alternateName":"SBPT","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/sbpt.org.br\/portal\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/sbpt.org.br\/portal\/#organization","name":"sbpt.org.br","url":"https:\/\/sbpt.org.br\/portal\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/sbpt.org.br\/portal\/#\/schema\/logo\/image\/","url":"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2026\/10\/logo-sbpt.png","contentUrl":"https:\/\/sbpt.org.br\/portal\/wp-content\/uploads\/2026\/10\/logo-sbpt.png","width":512,"height":512,"caption":"sbpt.org.br"},"image":{"@id":"https:\/\/sbpt.org.br\/portal\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/pneumosbpt","https:\/\/x.com\/pneumosbpt","https:\/\/www.linkedin.com\/company\/pneumosbpt\/","https:\/\/www.instagram.com\/pneumosbpt\/","https:\/\/www.youtube.com\/user\/socbraspneumol"]},{"@type":"Person","@id":"https:\/\/sbpt.org.br\/portal\/#\/schema\/person\/adba7f33cf32721354590c6f0eb852d4","name":"Comunica\u00e7\u00e3o SBPT","image":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/secure.gravatar.com\/avatar\/83068fab2f784f5c487104783a7006fb40e8fd85adc44189ac928b9e39fddad8?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/83068fab2f784f5c487104783a7006fb40e8fd85adc44189ac928b9e39fddad8?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/83068fab2f784f5c487104783a7006fb40e8fd85adc44189ac928b9e39fddad8?s=96&d=mm&r=g","caption":"Comunica\u00e7\u00e3o SBPT"},"url":"https:\/\/sbpt.org.br\/portal\/author\/anahelena\/"}]}},"_links":{"self":[{"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/posts\/15611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/comments?post=15611"}],"version-history":[{"count":0,"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/posts\/15611\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/media\/14596"}],"wp:attachment":[{"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/media?parent=15611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/categories?post=15611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sbpt.org.br\/portal\/wp-json\/wp\/v2\/tags?post=15611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}