{"id":15212,"date":"2020-04-07T20:04:17","date_gmt":"2020-04-07T20:04:17","guid":{"rendered":"https:\/\/sbpt.org.br\/portal\/?p=15212"},"modified":"2020-04-07T20:04:17","modified_gmt":"2020-04-07T20:04:17","slug":"resumo-cientifico-covid-2","status":"publish","type":"post","link":"https:\/\/sbpt.org.br\/portal\/resumo-cientifico-covid-2\/","title":{"rendered":"COVID-19: artigos chineses selecionados"},"content":{"rendered":"<p>Toda semana, a SBPT disponibiliza um resumo com artigos relevantes sobre o coronav\u00edrus, com o apoio da GSK. Leia os artigos sobre &#8220;Caracter\u00edsticas Cl\u00ednicas de Crian\u00e7as com Coronav\u00edrus em Hubei, China&#8221; e &#8220;Comorbidades e seus impactos em 1.590 pacientes com COVID-19 na China&#8221;.<\/p>\n<p style=\"text-align: justify\"><strong>CLINICAL CHARACTERISTICS OF CHILDREN WITH CORONAVIRUS DISEASE 2019 IN HUBEI, CHINA.<\/strong><\/p>\n<p style=\"text-align: justify\"><strong>Resumo<\/strong><\/p>\n<p style=\"text-align: justify\">Desde os primeiros casos da pneumonia por coronav\u00edrus (COVID-19) registrados em novembro de 2019 pouco se sabe a respeito de pacientes pedi\u00e1tricos. Zheng e coloaboradores publicaram no peri\u00f3dico Current Medical Science um estudo retrospectivo envolvendo 25 crian\u00e7as com diagn\u00f3stico positivo para COVID-19 internadas em 10 hospitais da regi\u00e3o metropolitana de Wuhan na China. Entre os achados:<\/p>\n<ul style=\"text-align: justify\">\n<li>Os sintomas mais comuns foram febre em 13 pacientes (52%) e tosse seca em 11 (44%).<\/li>\n<li>Tomografias de t\u00f3rax mostraram pulm\u00f5es normais em 8 casos (33,3%), acometimento unilateral em 5 casos (20,8%) e bilateral em 11 (45,8%).<\/li>\n<li>Quinze pacientes (60%), tiveram apresenta\u00e7\u00e3o cl\u00ednica como pneumonia leve.<\/li>\n<li>Dois casos (8%) mais cr\u00edticos, ambos em menores de 3 anos, foram submetidos ventila\u00e7\u00e3o mec\u00e2nica invasiva e administra\u00e7\u00e3o de corticoster\u00f3ides e imunoglobulina.<\/li>\n<\/ul>\n<p style=\"text-align: justify\">Em conclus\u00e3o, crian\u00e7as apresentam suscetibilidade ao COVID-19 semelhante aos adultos, mas com evolu\u00e7\u00e3o cl\u00ednica e resultados mais favor\u00e1veis. Contudo, pacientes com 3 anos ou menos necessitam aten\u00e7\u00e3o especial visto que a maior parte dos casos, incluindo os casos dois casos mais graves, est\u00e3o concentrados nessa faixa et\u00e1ria.<\/p>\n<p style=\"text-align: justify\"><a href=\"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s11596-020-2172-6.pdf\" target=\"_blank\" rel=\"noopener\">Clique aqui para acessar o artigo na \u00edntegra<\/a>.<\/p>\n<p style=\"text-align: justify\">Refer\u00eancia:<\/p>\n<p style=\"text-align: justify\">Zheng, F. et al. Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China. Curr Med Sci. 2020 Mar 24.<\/p>\n<p style=\"text-align: justify\"><strong>COMORBIDITY AND ITS IMPACT ON 1,590 PATIENTES WITH COVID-19 IN CHINA: A NATIONWIDE ANALYSIS.<\/strong><\/p>\n<p style=\"text-align: justify\"><strong>Resumo<\/strong><\/p>\n<p style=\"text-align: justify\">Estudo retrospectivo publicado no peri\u00f3dico BMJ por Wei-jie Guan e colaboradores teve como principal objetivo avaliar a presen\u00e7a comorbidades nos pacientes internados com COVID-19, e sua relev\u00e2ncia no desfecho cl\u00ednico destes pacientes. O estudo envolveu 575 hospitais em 31 prov\u00edcias da China e foram analisados dados de prontu\u00e1rios de 1.590 pacientes com diagn\u00f3stico confirmado de COVID-19 com m\u00e9dia de idade de 48.9 anos. Os principais resultados foram:<\/p>\n<ul style=\"text-align: justify\">\n<li>Sintomas mais comuns foram febre (88,0%), tosse seca (70,2%), fadiga (42,8%) e tosse produtiva (36.0%).<\/li>\n<li>Dezesseis por cento dos pacientes apresentaram a forma grave da doen\u00e7a.<\/li>\n<li>Comorbidades foram reportadas em 399 (25,1%), dentro destes 130 (8,2%) tinham mais de uma comorbidade.<\/li>\n<li>A frequ\u00eancia da forma mais grave foi maior em pacientes com comorbidades (32,8% <em>vs<\/em> 10,3%), com mais dispneia (41,4% <em>vs<\/em> 17,8%) e mais altera\u00e7\u00f5es em tomografia de t\u00f3rax (29,2% <em>vs<\/em> 15,1%).<\/li>\n<li>Com ajuste de idade pacientes com DPOC, diabetes, hipertens\u00e3o e\/ou malignidade apresentam maiores chances de interna\u00e7\u00e3o em UTI, ventila\u00e7\u00e3o invasiva ou morte.<\/li>\n<\/ul>\n<p style=\"text-align: justify\">Os autores conclu\u00edram que a presen\u00e7a de comorbidades pode predispor a um pior desfecho cl\u00ednico, sendo um dado valioso para estratificar risco na admiss\u00e3o hospitalar desses pacientes.<\/p>\n<p style=\"text-align: justify\"><a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.02.25.20027664v1.full.pdf+html\" target=\"_blank\" rel=\"noopener\">Clique aqui para acessar o artigo na \u00edntegra.<\/a><\/p>\n<p style=\"text-align: justify\">Refer\u00eancia:<\/p>\n<p style=\"text-align: justify\">Wei-jie Guan et al. Comorbidity and its impact on 1,590 patients with COVID-19 in China: A Nationwide Analysis. MedRxiv 2020.<\/p>\n<p style=\"text-align: justify\">PM-BR-FVU-WCNT-200007-ABR\/20<\/p>\n<hr>\n<p style=\"text-align: center\">Apoio:<\/p>\n<p><a href=\"https:\/\/d1xe7tfg0uwul9.cloudfront.net\/sbpt-portal\/wp-content\/uploads\/2018\/11\/GSK_LOS_PORTUGUESE_RGB.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-11208\" src=\"https:\/\/d1xe7tfg0uwul9.cloudfront.net\/sbpt-portal\/wp-content\/uploads\/2018\/11\/GSK_LOS_PORTUGUESE_RGB-150x150.png\" alt=\"\" width=\"77\" height=\"77\"><\/a><\/p>\n<!-- AddThis Advanced Settings generic via filter on the_content --><!-- AddThis Share Buttons generic via filter on the_content -->","protected":false},"excerpt":{"rendered":"<p>Toda semana, a SBPT disponibiliza um resumo com artigos relevantes sobre o coronav\u00edrus, com o apoio da GSK. Leia os artigos sobre &#8220;Caracter\u00edsticas Cl\u00ednicas de Crian\u00e7as com Coronav\u00edrus em Hubei, China&#8221; e &#8220;Comorbidades e seus impactos em 1.590 pacientes com COVID-19 na China&#8221;. CLINICAL CHARACTERISTICS OF CHILDREN WITH CORONAVIRUS DISEASE 2019 IN HUBEI, CHINA. Resumo [&hellip;]<!-- AddThis Advanced Settings generic via filter on get_the_excerpt --><!-- AddThis Share Buttons generic via filter on get_the_excerpt --><\/p>\n","protected":false},"author":3,"featured_media":15145,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"ngg_post_thumbnail":0,"footnotes":""},"categories":[68],"tags":[117,118,778],"class_list":["post-15212","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias","tag-coronavirus","tag-covid-19","tag-sars-cov-2"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>COVID-19: artigos chineses selecionados<\/title>\n<meta name=\"description\" content=\"Toda semana, a SBPT disponibiliza um resumo com artigos relevantes sobre o coronav\u00edrus, com o apoio da GSK. 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